Hnf4g | hepatocyte nuclear factor 4, gamma
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Hearing/vestibular/ear Renal/urinary system
17 No significant impact
5 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal auditory brainstem response | 1 supporting dataset | Hnf4gem1(IMPC)Mbp | homozygote | Early adult | 5.64x10-5 | ||
| small kidney | 1 supporting dataset | Hnf4gem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Hnf4gem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Hnf4g mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Hnf4g.
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| Hnf4gem1(IMPC)Mbp | Exon Deletion | | mouse |
| Hnf4gtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Hnf4gtm39941(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Hnf4gtm39941(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Hnf4gtm39941(L1L2_Pgk_PM) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Hnf4gtm39941(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |